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Article Reference Transdifferentiation of macrophages into fibroblasts as a result of Schistosoma mansoni infection.
The possibility of transdifferentiation of macrophages into fibroblasts which could be at the origin of fibrotic tissue in schistosome-infected mice was studied using immunocytochemical techniques. Macrophage cell samples extracted from the peritoneal cavity of schistosome-infected mice were fractionated on a Percoll gradient. The cultures were purified by treatment with a trypsin solution to eliminate any fibroblasts possibly collected along with the macrophages. Immunocytochemical methods were then used to characterize the cells at differentpoints in time. The fibroblastic property of the morphologically transformed cells was confirmed by their positive labeling with the anti-procollagen antibody. However, these cells still possessed the mac-1 and mac-2 antigens which characterize the monomacrophage line.
Located in Library / No RBINS Staff publications
Article Reference Transposable elements and asexual reproduction
Located in Library / RBINS Staff Publications
Article Reference Transposable elements in Ostracoda (Crustacea)
Located in Library / RBINS Staff Publications
Article Reference Traumatism in the wild animals kept and offered at predynastic Hierakonpolis, Upper Egypt
A description is given of the violence related pathologies that are observed in a number of wild mammals that were buried in the predynastic cemetery HK6 at Hierakonpolis, Upper Egypt. Unlike other predynastic graveyards, where only domestic cattle, sheep, goat and dogs are interred, the elite cemetery HK6 yielded also a wide variety of wild species that were buried as part of extensive mortuary complexes surrounding the graves of the highest local elite. The animals were interred, singly or in groups, often in graves of their own, but some also accompany human burials. Pathologies were found on the skeletons of 20 of the 38 wild animals discovered thus far, namely in 15 anubis baboons (Papio anubis), one leopard (Panthera pardus), one jungle cat (Felis chaus), one hartebeest (Alcelaphus buselaphus), one aurochs (Bos primigenius) and one hippo (Hippopotamus amphibius). Most of the pathologies are healed fractures resulting from violent blows, and a smaller proportion seems to be related to tethering. These conditions indicate that the animals were held in captivity for a prolonged period of time after their capture. The type and frequency of the encountered deformations differ from those seen in wild animals from other, more recent Egyptian cemeteries (Abydos, Tuna el-Gebel, Gabanet el-Giroud, Saqqara) where mainly metabolic disorders are observed that have been attributed to chronic malnutrition and to vitamin D deficiency as a result of inadequate housing in a dark environment. Keywords: archaeozoology - palaeopathology - bone fracture - hartebeest - aurochs - baboon - leopard - jungle cat.
Located in Library / RBINS Staff Publications
Article Reference Tree-dwelling ant survey (Hymenoptera, Formicidae) in Mitaraka, French Guiana
Located in Library / RBINS Staff Publications 2019
Article Reference Treeline and timberline dynamics on the northern and southern slopes of the Retezat Mountains (Romania) during the late glacial and the Holocene
Located in Library / RBINS Staff Publications 2018
Article Reference Treeline and timberline dynamics on the northern and southern slopes of the Retezat Mountains (Romania) during the late glacial and the Holocene
Abstract To investigate treeline and timberline dynamics in the Retezat Mountains (Romanian Carpathians), late glacial and Holocene sediment sequences from four lakes were studied. The south and north slopes of the mountain range were compared using two lakes from the north flank (Lake Brazi, 1740 m a.s.l. and Lake Gales, 1990 m a.s.l) and two from the south flank (Lake Lia, 1910 m a.s.l. and Lake Bucura, 2040 m a.s.l.). Macrofossil and stomata analyses were performed to assess changes in the local vegetation, supplemented by pollen, charcoal and loss-on-ignition analyses. Our results show that treeline reached Lake Brazi on the northern side during the late glacial (ca. 14,000 cal yr BP) and then Lake Gales between 11,000 and 10,800 cal yr BP. During the early Holocene the upper limit of closed forest, the timberline, reached and passed Lake Brazi and has stayed above it since, but it has never reached Lake Gales at 1990 m a.s.l. The expansion of Larix decidua in the late glacialand early Holocene around Lake Brazi is unique. Stomata and macrofossils of Abies alba are also more abundant in the northern records. On the southern flank, treeline reached Lake Lia at around 12,000 cal yr BP, and was either very close to or at the elevation of Lake Bucura between ca. 8600 and 3000 cal yr BP. Timberline reached Lake Lia at ca. 8000 cal yr BP, some 3000 years after Lake Brazi, only 170 m lower on the north slope. Local fire events delayed the advance of timberline around Lake Lia in the early Holocene in a dry continental climate. The surrounding forest was dominated by Picea abies with individuals of Pinus cembra and stands of P. mugo until about 3000 cal yr \BP\ when timberline retreated below the lake. Maximum elevation of timberline was attained between ca. 8000 and 3000 cal yr BP, after which it descended in response to climate cooling. Regional climate change appears to be the main driver of treeline dynamics, but it was modified by local climatic differences due to slope aspect. The first signs of human disturbance appeared ca. 4200 cal yr BP, when naturally open areas were used as alpine pastures. Human impact in the treeline ecotone, mainly burning and grazing, was intensified after ca. 2600 cal yr BP, contributing to the widening of the ecotone and the lowering of the timberline.
Located in Library / RBINS Staff Publications 2017
Article Reference Tremadocian and Floian (Ordovician) linguliformean brachiopods from the Stavelot–Venn Massif (Avalonia; Belgium and Germany)
Located in Library / RBINS Staff Publications 2022
Article Reference Tributyltin: A Bottom–Up Regulator of the Crangon crangon Population?
The restrictions and the concerted action of the global ban on the use and presence of tributyltin (TBT) in marine applications to protect ecosystems in the marine environment in 2008 was mainly based on the economic impact on shellfish industries and the dramatic extinction of local mollusk populations in the past. In contrast to the vast datasets on effects on mollusks, the knowledge on impacts on species from other taxa remained in the uncertain until almost two decades ago. The assumption on a long-term TBT-mediated pernicious metabolic bottom–up regulation of the crustacean Crangon crangon population was provoked by the outcome of an EU-project ‘Sources, Consumer Exposure and Risks of Organotin Contamination in Seafood.’ This study reported high TBT body burdens in C. crangon in 2003, at the start of the transition period to the global ban. Experimental research on the TBT impact in C. crangon focused on agonistic interference with natural ecdysteroid hormones at the metabolic pathways regulating growth and reproduction and the biogeochemical distribution of the chemical. In this paper, metabolic, topical and population-relevant biological endpoints in C. crangon and other crustaceans are evaluated in relation to the temporal and spatial trends on TBT’s occurrence and distribution in the field during and after the introduction of the tributyltin restrictions and endocrine-related incidents. Arguments are forwarded to relate the German Bight incident on growth and reproduction failure in the C. crangon population, despite the lack of direct evidence, to the pernicious impact of tributyltin in 1990/91 and previous years. The extreme occurrence of TBT in C. crangon from other parts of the southern North Sea and evidence on the high body burdens as dose metrics of exposure also feeds the suspicion on detrimental impacts in those areas. This paper further demonstrates the complexity of distinguishing and assessing the individual roles of unrelated stressors on a population in an integrated evaluation at the ecosystem level.
Located in Library / RBINS Staff Publications 2019
Inbook Reference Trictenotomidae. Catalogue of species
Located in Library / RBINS Staff Publications 2020