The dispersal of domestic cats from North Africa to Europe around 2000 years ago

The domestic cat (Felis catus) descends from the African wildcat Felis lybica lybica. Its global distribution alongside humans testifies to its successful adaptation to anthropogenic environments. Uncertainty remains regarding whether domestic cats originated in the Levant, Egypt, or elsewhere in the natural range of African wildcats. The timing and circumstances of their dispersal into Europe are also unknown. In this study, the analysis of 87 ancient and modern cat genomes suggests that domestic cats did not spread to Europe with Neolithic farmers. Conversely, they were introduced to Europe around 2000 years ago, probably from North Africa. In addition, a separate earlier introduction (first millennium before the common era) of wildcats from Northwest Africa may have been responsible for the present-day wild population in Sardinia. Tracing the origins of domestic cats (Felis catus) has been limited by a lack of ancient DNA for these animals, as well by their morphological similarity to the African wildcat (F. lybica lybica) and European wildcat (F. sylvestris). De Martino et al. generated low- to medium-coverage genomes for 87 ancient, museum, and modern cats (see the Perspective by Losos). They found that domestic cats are most genetically similar to African wildcats, although there has been widespread gene flow between wild and domestic populations. European samples that cluster with domestic cats only appear in the 1st century CE, suggesting a later dispersal of domestic cats than previously thought. Although broader sampling is needed, this study shows the complexity of population dynamics that is often revealed when looking beyond mitochondrial DNA.